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Antigenic Specificity | THRA, N-terminus |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 25 µL |
Concentration | 0.89 mg/mL |
Applications | ELISA, Immunohistochemistry, IF Microscopy, Immunoprecipitation, Western Blot. This affinity purified antibody has been tested for use in ELISA and western blotting. |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This product was affinity purified from monospecific antiserum by immunoaffinity chromatography. This antibody reacts with human THRA protein and recognizes THRA isoform 1. A BLAST analysis was used to suggest cross-reactivity with THRA from mouse, human and rat based on a 100% homology with the immunizing sequence. Cross-reactivity with THRA from other sources and isoforms may occur but has not been determined. |
Immunogen | This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to a region near the amino terminus of human THRA isoform 1 protein. |
Other Names | rabbit anti-THRA antibody, rabbit anti-Thyroid hormone receptor alpha antibody, Nuclear receptor subfamily 1 group A member 1, c-erbA-alpha, c-erbA-1, V-erbA-related protein 7, EAR7, ERBA1, NR1A1, THRA1, THRA2 |
Gene, Accession # | THRA, Gene ID: 7067, NCBI: 40806160, UniProt: P10827-2 |
Catalog # | 600-401-A38S |
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Order / More Info | THRA, N-terminus Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | Lopez-Juarez, A., Remaud, S., Hassani, Z., Jolivet, P., Pierre Simons, J., Sontag, T., ... & Demeneix, B. A. (2012). Thyroid Hormone Signaling Acts as a Neurogenic Switch by Repressing Sox2 in the Adult Neural Stem Cell Niche. Cell stem cell, 10(5), 531-543.Contreras-Jurado C, Garcia-Serrano L, Martinez-Fernandez M, Ruiz-Llorente L, Paramio JM, Aranda A. (2014) Impaired hair growth and wound healing in mice lacking thyroid hormone receptors. PLoS One. 2014 Sep 25;9(9):e108137. doi: 10.1371/journal.pone.0108137. eCollection 2014.Mishra A, Zhu XG, Ge K, Cheng SY. (2010) Adipogenesis is differentially impaired by thyroid hormone receptor mutant isoforms. J Mol Endocrinol. 2010 Apr;44(4):247-55. doi: 10.1677/JME-09-0137. Epub 2010 Jan 15. |
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