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| Product Name | Chemokine (C-C Motif) Ligand 17 (CCL17) (Active) protein |
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| Description | Thymus and activation regulated chemokine (TARC) is a novel CC chemokine, also called CCL17, recently identified using a signal sequence trap method. CCL17 cDNA encodes a highly basic 94 amino acid (a.a.) residue precursor protein with a 23 a.a. residue signal peptide that is cleaved to generate the 71 a.a. residue mature secreted protein. Among CC chemokine family members, CCL17 has approximately 24 - 29% amino acid sequence identity with RANTES, MIP-1alpha, MIP-1beta, MCP-1, MCP-2, MCP-3 and I-309. CCL17 is constitutively expressed in thymus, and at a lower level in lung, colon, and small intestine. CCL17 is also transiently expressed in stimulated peripheral blood mononuclear cells. Recombinant CCL17 has been shown to be chemotactic for T cell lines but not monocytes or neutrophils. CCL17 was recently identified to be a specific functional ligand for CCR-4, a receptor that is selectively expressed on T cells.Synonyms: C-C motif chemokine 17, Small-inducible cytokine A17, Thymus and activation-regulated chemokine, CC chemokine TARC, ABCD-2, SCYA17, A-152E5.3, MGC138271, MGC138273. |
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| Size | 5 µg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | CCL17|A-152E5.3|ABCD-2|SCYA17|TARC|Abcd-2|Scya17|Scya17l|Tarc |
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| Gene, Accession, CAS # | Gene ID: 20295 |
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| Catalog # | ABIN2018392 |
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| Order / More Info | Chemokine (C-C Motif) Ligand 17 (CCL17) (Active) protein from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | n/a |
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