| 产品详情 |
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| Product Name | Tumor Necrosis Factor Receptor Superfamily, Member 1B (TNFRSF1B) peptide |
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| Description | The P75 TNFR (TNFR-II) membrane receptor is expressed on most mammalian cells. The actions of TNF-alpha are mediated via a 55,000/60,000 Da receptor (TNFR-I) and a 75,000/80,000 Da receptor (TNFR-II). The cleavage site for TNFR-II is Val192-is193, which is 14 amino acids from the cysteine-rich extracellular domain, compared with six amino acids for TNFR-I. The P75-TNFR directly mediates distinct cellular responses such as proliferation of T and B cells, activation of NF-beta, and induction of cytotoxicity. A recent study has described an assay using cells expressing TNFR-II at the cell surface to partially characterize a soluble metallosecretase that is itself secreted into the media upon phorbol ester stimulation of the cells. |
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| Size | 5 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | MGC83471|LOC100218184|TRAF2|TANK|TNF-RII/TNFRSF1B|TNFRSF1B|CD120b|TBPII|TNF-R-II|TNF-R75|TNFBR|TNFR1B|TNFR2|TNFR80|p75|p75TNFR|TNF-R2|TNF-alphaR2|TNFRII|TNFalpha-R2|Tnfr-1|Tnfr2|TNFR-II |
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| Gene, Accession, CAS # | Gene ID: 21938, 7133, 156767, 100723273, 395083, 100037306 |
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| Catalog # | ABIN399687 |
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| Order / More Info | Tumor Necrosis Factor Receptor Superfamily, Member 1B (TNFRSF1B) peptide from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | n/a |
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