| 产品详情 |
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| Product Name | Tumor Necrosis Factor Receptor Superfamily, Member 13B (TNFRSF13B) (Extracellular Domain), (AA 2-118) (Active) protein (Fc Tag) |
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| Description | B-cell activating factor belonging to the TNF family receptor (BAFF-R), B-cell maturation antigen (BCMA), and transmembrane activator and calcium modulator and cyclophilin ligand interactor (TACI) play critical functions in promoting B-cell survival by engaging the ligands a proliferation-inducing ligand (APRIL) and/or BAFF. TACI is predominantly expressed on peripheral blood B cells and interacts with the B cell activating factor (BAFF) of ligands and a proliferation inducing ligand (APRIL), which are expressed by numerous cell types, including dendritic cells, macrophages and neutrophils. TNFRSF13B, the gene, which encodes TACI is mutated in nearly 10% of patients with common variable immune deficiency (CVID), an antibody deficiency syndrome characterized by loss of memory B cells and plasma cells. |
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| Size | 50 µg |
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| Concentration | n/a |
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| Applications | SDS-PAGE (SDS) |
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| Other Names | TNFRSF13B|CD267|CVID|CVID2|RYZN|TACI|TNFRSF14B|1200009E08Rik|Taci |
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| Gene, Accession, CAS # | Gene ID: 23495, 57916 |
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| Catalog # | ABIN1344232 |
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| Order / More Info | Tumor Necrosis Factor Receptor Superfamily, Member 13B (TNFRSF13B) (Extracellular Domain), (AA 2-118) (Active) protein (Fc Tag) from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | PubMed: 22355399 |
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