| 产品详情 |
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| Product Name | Tumor Necrosis Factor Receptor Superfamily, Member 10b (TNFRSF10B) (Extracellular Domain), (AA 52-212) (Active) protein (Fc Tag) |
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| Description | TRAIL-R2 (DR5, CD262) is a receptor for the cytotoxic ligand TRAIL. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF-kappaB. |
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| Size | 3 x 50 µg |
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| Concentration | n/a |
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| Applications | SDS-PAGE (SDS) |
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| Other Names | TNFRSF10B|dr5|cd262|killer|trick2|trickb|xDR-M1|xDR-M2|ztnfr9|trailr2|trick2a|trick2b|CD262|DR5|KILLER|KILLER/DR5|TRAIL-R2|TRAILR2|TRICK2|TRICK2A|TRICK2B|TRICKB|ZTNFR9|Ly98|MK |
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| Gene, Accession, CAS # | Gene ID: 8795 |
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| Catalog # | ABIN1344265 |
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| Order / More Info | Tumor Necrosis Factor Receptor Superfamily, Member 10b (TNFRSF10B) (Extracellular Domain), (AA 52-212) (Active) protein (Fc Tag) from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | n/a |
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