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Product Name | Recombinant Human UDP-glucose 4-epimerase (GALE) |
Description | Purity > 90% as determined by SDS-PAGE. MW: 54.3kDa. Full Length: 1-348aa. N-terminal 6xHis-SUMO-tagged. Homo sapiens (Human). Catalyzes two distinct but analogous reactions: the reversible epimerization of UDP-glucose to UDP-galactose and the reversible epimerization of UDP-N-acetylglucosamine to UDP-N-acetylgalactosamine. The reaction with UDP-Gal plays a critical role in the Leloir pathway of galactose catabolism in which galactose is converted to the glycolytic intermediate glucose 6-phosphate. It contributes to the catabolism of dietary galactose and enables the endogenous biosynthesis of both UDP-Gal and UDP-GalNAc when exogenous sources are limited. Both UDP-sugar interconversions are important in the synthesis of glycoproteins and glycolipids. |
Size | 100ug |
Concentration | n/a |
Applications | RUO |
Other Names | Galactowaldenase |
Gene, Accession, CAS # | GALE, UniProt: Q14376 |
Catalog # | RPC22967 |
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Order / More Info | Recombinant Human UDP-glucose 4-epimerase (GALE) from BIOMATIK |
Product Specific References | n/a |
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