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| Product Name | Apo-J/Clusterin |
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| Description | Apoliprotein J (APO-J), also named Clusterin, is a 75-80 kD disulfide-linked heterodimeric protein. The precursor polypeptide chain is cleaved proteolytically to remove the 22-mer secretory signal peptide and subsequently between residues 227/228 to generate the a and b chains. These are assembled in anti-parallel to give a heterodimeric molecule in which the cysteine-rich centers are linked by five disulfide bridges and are flanked by two predicted coiled-coil a-helices and three predicted amphipathic a-helices. Clusterin is up- or down regulated on the mRNA or protein level in many pathological and clinically relevant situations including cancer, organ regeneration, infection, Alzheimer disease, retinitis pigmentosa, myocardial infarction |
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| Size | 500 µg |
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| Concentration | n/a |
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| Applications | RUO |
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| Other Names | CLI, AAG4, KUB1, SGP2, SGP-2, SP-40, TRPM2, , MGC24903, Clusterin, Apolipoprotein J, Apo-J, Apolipoprotein, apolipoproteins, Aging-associated gene 4 protein, Complement cytolysis inhibitor, Complement-associated protein SP-40,40, Ku70-binding protein 1, NA1/NA2, Testosterone-repressed prostate message 2 |
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| Gene, Accession, CAS # | TRPM-2, Gene ID: 1191, Accession: P10909 |
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| Catalog # | 4325-500 |
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| Order / More Info | Apo-J/Clusterin from BIOVISION, INC. |
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| Product Specific References | n/a |
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