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Product Name | Integral Membrane Protein 2B (ITM2B) (AA 76-266) protein (His tag) |
Description | Integral Membrane Protein 2B (ITM2B) is expressed in the Golgi and on the cell surface. ITM2B forms homodimer through disulfide-linked interaction with SPPL2A, SPPL2B and APP. ITM2B is expressed in brain and the other tissues. Defects in ITM2B cause cerebral amyloid angiopathy ITM2B-related type 1(CAA-ITM2B1) and amyloid angiopathy ITM2B-related type 2(CAA-ITM2B2). CAA-ITM2B1 is characterized by amyloid deposition in the walls of cerebral blood vessels and neurodegeneration in the central nervous system. CAA-ITM2B2 characterized by amyloid deposition in the walls of the blood vessels of the cerebrum, choroid plexus, cerebellum, spinal cord and retina. Synonyms: Integral Membrane Protein 2B, Immature BRI2, imBRI2, Protein E25B, Transmembrane Protein BRI, Bri, ITM2B, BRI, BRI2 |
Size | 10 µg |
Concentration | n/a |
Applications | n/a |
Other Names | itm2b|zgc:55770|zgc:85688|wu:fc05f02|MGC52745|MGC76131|ITM2B|Bri|imBRI2|ABRI|BRI|BRI2|BRICD2B|E25B|E3-16|FBD|AI256040|Bri2|Bricd2b|D14Sel6|E25BMM |
Gene, Accession, CAS # | Gene ID: 9445 |
Catalog # | ABIN2115496 |
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Order / More Info | Integral Membrane Protein 2B (ITM2B) (AA 76-266) protein (His tag) from ANTIBODIES-ONLINE GmbH |
Product Specific References | n/a |
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