| 产品详情 |
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| Product Name | Sotrastaurin |
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| Description | A PKC inhibitor that displays immunosuppressive activity, blocking T cell activation through the disruption of downstream NF-κB signaling; inhibits PKCα, βI, δ, ε, η, and θ with Ki values of 0.95, 0.64, 2.1, 3.2, 1.8, and 0.22 nM, respectively; also inhibits GSK3α and GSK3β (IC50s = 229 and 172 nM, respectively), which activates Wnt/β-catenin signaling and is important for adult stem cell maintenance |
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| Size | 10 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | AEB071 |
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| Gene, Accession, CAS # | CAS: 425637-18-9 |
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| Catalog # | 16726-10 |
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| Order / More Info | Sotrastaurin from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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| 产品资料 |
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