产品详情 |
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Antigenic Specificity | CD40 Ligand (CD40LG) |
Clone | polyclonal |
Host Species | Goat |
Reactive Species | human |
Isotype | n/a |
Format | biotin conjugate |
Size | 50 µg |
Concentration | n/a |
Applications | Enzyme Immunoassay (EIA),Western Blotting (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CD40 ligand (CD40L) is a 33 kDa type II membrane glycoprotein expressed mainly on the cell surface of activated T lymphocytes, but also exists as a soluble form extracellularly. CD40L is the ligand for CD40, a member of the TNF superfamily, which is expressed on the cell surface of B cells, macrophages/monocytes, dendritic cells, vascular endothelial cells, and epithelial cells. CD40L plays an important role in B cell proliferation, antibody class switching, modulation of apoptosis in the germinal center through interaction with B cells expressing CD40, and activation of CD4+ T cells. Mutation within the CD40L gene is linked to hyper IgM syndrome, an X linked immunodeficiency disease that is characterized by elevated level of serum IgM and decreased level of other isotypes.Synonyms: CD40 ligand, CD40-L, CD40LG, GP39, T-cell antigen Gp39, TNF-related activation protein, TNFSF5, TRAP, Tumor necrosis factor ligand superfamily member 5 |
Immunogen | Highly pure (> 98%) E.coli derived recombinant Human sCD40L |
Other Names | CD154|cd40l|CD40L|HIGM1|IGM|IMD3|T-BAM|TNFSF5|TRAP|gp39|hCD40L|CD40-L|Cd40l|Ly-62|Ly62|Tnfsf5 |
Gene, Accession # | Gene ID: 959 |
Catalog # | ABIN181577 |
Price | |
Order / More Info | CD40 Ligand (CD40LG) Antibody from ANTIBODIES-ONLINE GmbH |
Product Specific References | n/a |
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