产品详情 |
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Antigenic Specificity | CD40 Ligand (CD40LG) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 50 µg |
Concentration | n/a |
Applications | ELISA,Blocking Antibody (Inhibition),Western Blotting (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CD40, a member of the TNF receptor family, is a cell surface protein expressed on B cells, dendritic cells, monocytes, thymic epithelial cells and, at low levels, on T cells. Signaling though CD40 plays an important role in the proliferation and differentiation of B cells, and is critical for immunoglobulin (Ig) class switching. The membrane-anchored CD40-Ligand is expressed almost exclusively on activated CD4+ T lymphocytes. Failure to express CD40L leads to immunodeficiency with hyper-IgM, a disease characterized by failure to produce IgG, IgA and IgE. The human CD40L gene codes for a 261 amino acid type II transmembrane protein, which contains a 22 amino acid cytoplasmic domain, a 24 amino acid transmembrane domain, and a 215 amino acid extracellular domain. |
Immunogen | CD40 L antibody was raised in rabbit using highly pure recombinant human sCD40 as the immunogen. |
Other Names | CD154|cd40l|CD40L|HIGM1|IGM|IMD3|T-BAM|TNFSF5|TRAP|gp39|hCD40L|CD40-L|Cd40l|Ly-62|Ly62|Tnfsf5 |
Gene, Accession # | Gene ID: 959 |
Catalog # | ABIN636589 |
Price | |
Order / More Info | CD40 Ligand (CD40LG) Antibody from ANTIBODIES-ONLINE GmbH |
Product Specific References | n/a |
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