| 产品详情 |
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| Antigenic Specificity | XRCC1 |
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| Clone | 2H4 |
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| Host Species | Recombinant Mouse |
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| Reactive Species | human |
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| Isotype | IgG2a, κ |
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| Format | unconjugated |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | ELISA, IF, WB |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Mouse Anti-XRCC1 Recombinant Antibody (2H4). Provided herein is a Mouse monoclonal antibody against Human XRCC1. The antibody, clone 2H4, can be used for immunoassay techniques, such as ELISA, IF, WB. XRCC1 is involved in the efficient repair of DNA single-strand breaks formed by exposure to ionizing radiation and alkylating agents. XRCC1 interacts with DNA ligase III, polymerase beta and poly (ADP-ribose) polymerase to participate in the base excision repair pathway. It may play a role in DNA processing during meiogenesis and recombination in germ cells. A rare microsatellite polymorphism in XRCC1 is associated with cancer in patients of varying radiosensitivity. |
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| Immunogen | XRCC2 (AAH42137, 1 a.a. ~ 280 a.a) full-length recombinant protein with GST tag. Immunogen sequence: MCSAFHRAES GTELLARLEG RSSLKEIEPN LFADEDSPVH GDILEFHGPE GTGKTEMLYH LTARCILPKS EGGLEVEVLF IDTDYHFDML RLVTILEHRL SQSSEEIIKY CLGRFFLVYC SSSTHLLLTL YSLESMFCSH PSLCLLILDS LSAFYWIDRV NGGESVNLQE STLRKCSQCL EKLVNDYRLV LFATTQTIMQ KASSSSEEPS HASRRLCDVD IDYRPYLCKA WQQLVKHRMF FSKQDDSQSS NQFSLVSRCL KSNSLKKHFF IIGESGVEFC |
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| Other Names | RCC; SCAR26 |
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| Gene, Accession # | Gene ID: 7515, UniProt: P18887 |
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| Catalog # | CBMAB-X0172-YC |
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| Price | |
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| Order / More Info | XRCC1 Antibody from CREATIVE BIOLABS |
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| Product Specific References | n/a |
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