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Antigenic Specificity | Programmed Cell Death 4 (Neoplastic Transformation Inhibitor) (PDCD4) (aa 351-368), (C-Term) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 100 µg |
Concentration | n/a |
Applications | Western Blotting (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Programmed cell death protein 4(PDCD4) is a protein that in humans is encoded by the PDCD4 gene. It is mapped to 10q25.2. This gene is a tumor suppressor and encodes a protein that binds to the eukaryotic translation initiation factor 4A1 and inhibits its function by preventing RNA binding. It also encodes a protein localized to the nucleus in proliferating cells. Expression of this gene is modulated by cytokines in natural killer and T cells. The gene product is though to play a role in apoptosis but the specific role has not yet been determined. |
Immunogen | A synthetic peptide corresponding to a sequence at the C-terminus of human PDCD4(351-368aa LKELEVPHFHHELVYEAI), identical to the related mouse and rat sequences. |
Other Names | h731|MGC69337|PDCD4|D19Ucla1|Ma3|Tis|Dug|H731 |
Gene, Accession # | Gene ID: 27250 |
Catalog # | ABIN1889199 |
Price | |
Order / More Info | Programmed Cell Death 4 (Neoplastic Transformation Inhibitor) (PDCD4) (aa 351-368), (C-Term) Antibody from ANTIBODIES-ONLINE GmbH |
Product Specific References | PubMed: 9759869 |