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| Product Name | Recombinant Human BD-4 Protein |
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| Description | Defensins (alpha and beta) are cationic peptides with a broad spectrum of antimicrobial activity that comprise an important arm of the innate immune system. The α-defensins are distinguished from the β-defensins by the pairing of their three disulfide bonds. To date, six human β-defensins have been identified; BD-1, BD-2, BD-3, BD-4, BD-5 and BD-6. β-defensins are expressed on some leukocytes and at epithelial surfaces. In addition to their direct antimicrobial activities, they can act as chemoattractants towards immature dendritic cells and memory T cells. The β-defensin proteins are expressed as the C-terminal portion of precursors and are released by proteolytic cleavage of a signal sequence and in some cases, a propeptide sequence. β-defensins contain a six-cysteine motif that forms three intra-molecular disulfide bonds. BD-4 is expressed in testis, stomach, uterus, neutrophils, thyroid, lung and kidney. In addition to its direct antimicrobial activities, BD-4 is chemoattractant towards human blood monocytes. Recombinant human BD-4 is a 6.0 kDa protein containing 50 amino acid residues. |
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| Size | Various Sizes |
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| Concentration | n/a |
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| Applications | Cell Culture |
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| Other Names | Beta-defensin 104;Beta-defensin 4;BD-4;DEFB-4;hBD-4;Defensin, beta 104;DEFB104A;DEFB104, DEFB4;DEFB104B; Beta-defensin 104, BEFB4 |
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| Gene, Accession, CAS # | DEFB104A, UniProt: Q8WTQ1 |
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| Catalog # | PROTQ8WTQ1-1 |
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| Order / More Info | Recombinant Human BD-4 Protein from BOSTER BIO |
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| Product Specific References | n/a |
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