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| Product Name | Sepiapterin reductase, 1-261aa, Human, His tag, E Coli |
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| Description | MW: 30.2 kDa (281aa), confirmed by MALDI-TOF. Purity >95% by SDS-PAGE. Sepiapterin reductase (SPR) belongs to the short-chain dehydrogenase/reductase (SDR) family and also reduces various exogenous carbonyl compounds including phenylpropanedione. SPR is an essential enzyme for the biosynthesis of tetrahydrobiopterin, an essential cofactor for aromatic amino acid hydrolases including tyrosine hydroxylase, the rate-limiting enzyme in dopamine synthesis. Defects in SPR cause DOPA-responsive dystoni |
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| Size | 0.1 mg, 0.5 mg |
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| Concentration | 0.5 mg/ml (determined by Bradford assay) |
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| Applications | SDS-PAGE |
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| Other Names | [SPR; Sepiapterin reductase.] |
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| Gene, Accession, CAS # | SPR; SPR; SDR38C1; SPR, Gene ID: 6697, Accession: NP_003115 |
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| Catalog # | MBS203289 |
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| Order / More Info | Sepiapterin reductase, 1-261aa, Human, His tag, E Coli from MYBIOSOURCE INC. |
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| Product Specific References | Tobin JE., et al. (2007). Brain Res. 30:42-7.; Ohye T., et al. (1998). Biochem Biophys Res Commun. 251 (2):597-602.; |
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