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| Product Name | METTL1, 1-276aa, Human, His tag, E Coli |
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| Description | MW: 33.6kDa (296aa), confirmed by MALDI-TOF. Purity >90% by SDS-PAGE. METTL1 is known as tRNA (guanine-N (7)-)-methyltransferase which belongs to the methyltransferase superfamily. METTL1 shows high sequence similarity to yeast ORF YDL201w and has been shown to be inactivated by phosphorylation. This protein contains a conserved S-adenosylmethionine-binding motif and is inactivated by phosphylation. It catalyzes the formation of N (7)-methylguanine at position 46 (m7G46) in tRNA. Recombinant hum |
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| Size | 0.05 mg, 0.25 mg |
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| Concentration | 0.5 mg/ml (determined by Bradford assay) |
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| Applications | SDS-PAGE |
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| Other Names | [Methyltransferase like 1; TRM8; YDL201w] |
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| Gene, Accession, CAS # | METTL1, Gene ID: 4234, Accession: NP_005362 |
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| Catalog # | MBS203748 |
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| Order / More Info | METTL1, 1-276aa, Human, His tag, E Coli from MYBIOSOURCE INC. |
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| Product Specific References | Matsumoto K., et al. (2008) J. Biotechnol. 133: 453-460.; Alexandrov A., et al. (2002) RNA 8:1253-1266; |
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