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Antigenic Specificity | Prostaglandin E Receptor 1 (Subtype EP1), 42kDa (PTGER1) (aa 387-404), (C-Term) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 100 µg |
Concentration | n/a |
Applications | Western Blotting (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | PTGER1, Prostaglandin E Receptor 1, comprises 402 amino acids with a predicted molecular mass of 41, 858 and has the 7 predicted transmembrane-spanning domains common to all G protein-coupled receptors. The PTGER1 gene is mapped to chromosome 19p13.1. The protein encoded by this gene is a member of the G protein-coupled receptor family. This protein is one of four receptors identified for prostaglandin E2(PGE2). Through a phosphatidylinositol-calcium second messenger system, Gq proteins mediate this receptor's activity. Knockout studies in mice suggested a role of this receptor in mediating algesia and in regulation of blood pressure. Studies in mice also suggested that this gene may mediate adrenocorticotropic hormone response to bacterial endotoxin. |
Immunogen | A synthetic peptide corresponding to a sequence at the C-terminus of human Prostaglandin E Receptor EP1(387-404aa AWEASSLRSSRHSGLSHF). |
Other Names | PTGER1|42kDa|EP1|Ptgerep1 |
Gene, Accession # | Gene ID: 5731 |
Catalog # | ABIN1673057 |
Price | |
Order / More Info | Prostaglandin E Receptor 1 (Subtype EP1), 42kDa (PTGER1) (aa 387-404), (C-Term) Antibody from ANTIBODIES-ONLINE GmbH |
Product Specific References | PubMed: 8253813, 16247016, 11160156 |