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Product Name | Peptidylprolyl Isomerase C (Cyclophilin C) (PPIC) (AA 131-182) protein |
Description | Recombinant Human Cyclophilin C/CYPC is produced by our E. coli expression system. The target protein is expressed with sequence (Trp131-Asp182) of Human CYPC fused with a His tag at the N-terminus. Cyclophilin C is an enzyme (EC 5.2.1.8) found in both prokaryotes and eukaryotes that interconverts the cis and trans isomers of peptide bonds with the AA proline. Proline has an unusually conformationally restrained peptide bond due to its cyclic structure with its side chain bonded to its secondary amine nitrogen. Most AAs have a strong energetic preference for the trans peptide bond conformation due to steric hindrance, but prolines unusual structure stabilizes the cis form so that both isomers are populated under biologically relevant conditions. Proteins with prolyl isomerase activity include cyclophilin, FKBPs, and parvulin, although larger proteins can also contain prolyl isomerase domains. |
Size | 1 mg |
Concentration | n/a |
Applications | n/a |
Other Names | cypc|CyP-20c|CYPC |
Gene, Accession, CAS # | Gene ID: 5480 |
Catalog # | ABIN1096480 |
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Order / More Info | Peptidylprolyl Isomerase C (Cyclophilin C) (PPIC) (AA 131-182) protein from ANTIBODIES-ONLINE GmbH |
Product Specific References | n/a |
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