| 产品详情 |
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| Product Name | Peptidylprolyl Cis/trans Isomerase, NIMA-Interacting 1 (PIN1) (AA 22-255), (Extracellular Domain) peptide |
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| Description | Human Pin1 is a peptidyl-prolyl cis/trans isomerase (PPIase) that interacts with NIMA and essential for cell cycle regulation. Pin1 is nuclear PPIase containing a WW protein interaction domain, and is structurally and functionally related to Ess1/Ptf1, an essential protein in budding yeast. PPIase activity is necessary for Ess1/Pin1 function in yeast. Pin1 is thus an essential PPIase that regulates mitosis presumably by interacting with NIMA and attenuating its mitosis-promoting activity. Substrates of Pin1 include the mitotic regulators (Cdc25 phosphatase and NIMA ,PLK I, Wee, and Myt1 kinases), several transcription factors like beta-Catenin, c-Jun, and the tumor suppressor protein p53 , and some specific proteins like the RNA Pol II, the cytoskeleton protein tau, and the G1/S protein Cyclin D1. Alternative Names: Rotamase Pin1 protein, UBL5 protein, PPIase protein, Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 protein, Pin -1 protein, Pin -1, Pin 1, PPIase Pin1 protein, Pin 1 protein, PPIase Pin1 protein, Rotamase Pin1 protein, DOD protein, Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1, PIN1 protein, PIN1 protein, EC 5.2.1.8 protein, Pin 1, EC 5.2.1.8 protein |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | SDS-PAGE (SDS) |
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| Other Names | OTTMUSG00000014964|Pin1-ps1|Pin1l|dod|ubl5|pin1b|pin1|pin1a|DOD|UBL5|0610025L01Rik|D9Bwg1161e |
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| Gene, Accession, CAS # | Gene ID: 5300 |
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| Catalog # | ABIN934902 |
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| Order / More Info | Peptidylprolyl Cis/trans Isomerase, NIMA-Interacting 1 (PIN1) (AA 22-255), (Extracellular Domain) peptide from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | n/a |
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