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| Product Name | J9 |
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| Description | MW: 212.26. J9, in combination with dexamethasone inhibits cell growth in T-cell acute lymphoblastic leukemia (T-ALL) through the upregulation of the glucocorticoid receptor. Patients can develop glucocorticoid resistance rendering the treatment ineffective. J9 and its mechanism of action provides a useful strategy for overcoming the resistance. The EC50 of J9 in combination with dexamethasone is 28 uM. J9 alone was less toxic. |
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| Size | 10 mg |
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| Concentration | n/a |
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| Applications | RUO |
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| Other Names | 4-cyclopropyl-5-(pyridin-4-yl)pyrimidin-2-amine |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | abx076815 |
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| Price | |
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| Order / More Info | J9 from ABBEXA |
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| Product Specific References | n/a |
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| 产品资料 |
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