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| Product Name | Recombinant Human E3 ubiquitin-protein ligase CBL (CBL) , partial |
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| Description | MW: 99,633 Da. Purity >85% (SDS-PAGE). The cbl oncogene was first identified as part of a transforming retrovirus which induces mouse pre-B and pro-B cell lymphomas. As an adaptor protein for receptor protein-tyrosine kinases, it positively regulates receptor protein-tyrosine kinase ubiquitination in a manner dependent upon its variant SH2 and RING finger domains. Ubiquitination of receptor protein-tyrosine kinases terminates signaling by marking active receptors for degradation. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [E3 ubiquitin-protein ligase CBL; E3 ubiquitin-protein ligase CBL; E3 ubiquitin-protein ligase CBL; Cbl proto-oncogene; Casitas B-lineage lymphoma proto-oncogene; Proto-oncogene c-Cbl; RING finger protein 55; RING-type E3 ubiquitin transferase CBLCurated; Signal transduction protein CBL] |
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| Gene, Accession, CAS # | CBL, Gene ID: 867, Accession: NP_005179.2 |
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| Catalog # | MBS949435 |
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| Price | |
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| Order / More Info | Recombinant Human E3 ubiquitin-protein ligase CBL (CBL) , partial from MYBIOSOURCE INC. |
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| Product Specific References | n/a |
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