产品详情 |
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Antigenic Specificity | KHDRBS2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, rat |
Isotype | n/a |
Format | purified |
Size | 400 µl |
Concentration | n/a |
Applications | Western Blot: 1:1000 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | KHDRBS2 Polyclonal Antibody. RNA-binding protein that plays a role in the regulation of alternative splicing and influences mRNA splice site selection and exon inclusion. Binds both poly(A) and poly(U) homopolymers. Phosphorylation by PTK6 inhibits its RNA-binding ability (By similarity). Induces an increased concentration-dependent incorporation of exon in CD44 pre-mRNA by direct binding to purine-rich exonic enhancer. Can regulate alternative splicing of NRXN1 in the laminin G-like domain 6 containing the evolutionary conserved neurexin alternative spliced segment 4 (AS4) involved in neurexin selective targeting to postsynaptic partners. Regulates cell-type specific alternative splicing of NRXN1 at AS4 and acts synergystically with SAM68 |
Immunogen | n/a |
Other Names | KH domain-containing; RNA-binding; signal transduction-associated protein 2; Sam68-like mammalian protein 1; SLM-1; hSLM-1; KHDRBS2; SLM1 |
Gene, Accession # | Entrez: 170843, 202559; Uniprot: Q5VWX1, Q920F3 |
Catalog # | PA5-72167 |
Price | |
Order / More Info | KHDRBS2 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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