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| Product Name | Vascular Endothelial Growth Factor C (VEGFC) protein (His tag) |
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| Description | VEGF-C, also known as Vascular Endothelial Growth Factor Related Protein (VRP), is a recently discovered VEGF growth factor family member that is most closely related to VEGF-D. The rat VEGFC cDNA encodes a pre-pro-protein of 416 AA residues. It is almost identical to the mouse VEGF-C protein. Similar to VEGF-D, VEGF-C has a VEGF homology domain spanning the middle third of the precursor molecule and long N- and C-terminal extensions. In adults, VEGF-C is highly expressed in heart, placenta, ovary and small intestine. Recombinant rat VEGF-C, lacking the N- and C-terminal extensions and containing only the middle VEGF homology domain, forms primarily non-covalently linked dimers. This protein is a ligand for both VEGFR-2/KDR and VEGFR-3/FLT -4. Since VEGFR-3 is strongly expressed in lymphatic endothelial cells, it has been postulated that VEGF-C is involved in the regulation of the growth and/or differentiation of lymphatic endothelium. Although recombinant rat VEGF-C is also a mitogen for vascular endothelial cells, it is much less potent than VEGF-A Synonyms: VEGF-C, Vascular endothelial growth factor C, VRP, Flt4 ligand, Flt4-L. |
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| Size | 2 µg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | VEGFC|vegf-c|xvegf-c|Flt4-L|VRP|AW228853|VEGF-C |
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| Gene, Accession, CAS # | Gene ID: 114111 |
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| Catalog # | ABIN804005 |
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| Order / More Info | Vascular Endothelial Growth Factor C (VEGFC) protein (His tag) from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | n/a |
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