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Product Name | Vascular Endothelial Growth Factor C (VEGFC) protein |
Description | VEGF-C, a member of the VEGF/PDGF family of structurally related proteins, is a potent angiogenic cytokine. It promotes endothelial cell growth, promotes lymphangiogesis, and can also affect vascular permeability. VEGF-C is expressed in various tissues, but is not produced in peripheral blood lymphocytes. It forms cell surfaced-associated non-covalent disulfide linked homodimers, and can bind and activate both VEGFR-2 (flk1) and VEGFR-3 (flt4) receptors. During embryogenesis, VEGF-C may play a role in the formation of the venous and lymphatic vascular systems. Both VEGF-C and VEGF-D are over-expressed in certain cancers, and the resulting elevated levels of VEGF-C or VEGF-D tend to correlate with increased lymphatic metastasis. Alternative Names: VRP protein, flt4 ligand protein, Vascular Endothelial Growth Factor-C protein |
Size | 20 µg |
Concentration | n/a |
Applications | n/a |
Other Names | VEGFC|vegf-c|xvegf-c|Flt4-L|VRP|AW228853|VEGF-C |
Gene, Accession, CAS # | Gene ID: 7424 |
Catalog # | ABIN935903 |
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Order / More Info | Vascular Endothelial Growth Factor C (VEGFC) protein from ANTIBODIES-ONLINE GmbH |
Product Specific References | n/a |
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