| 产品详情 |
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| Antigenic Specificity | B-Cell Linker (BLNK) (aa 171-356) |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | mouse |
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| Isotype | n/a |
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| Format | purified |
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| Size | 0.1 mg |
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| Concentration | n/a |
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| Applications | Western Blotting (WB) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | SLP65 / BLNK (SH2 domain-containing leukocyte-specific phosphoprotein of 65 kDa, B cell linker protein), also known as BASH, is an adaptor protein that plays key role in B cell activation initiated by cross-linking the B cell receptor (BCR). Phosphorylated by Syk tyrosine kinase, SLP65 serves as a scaffold for Btk tyrosine kinase, Vav1 guanine nucleotide exchange factor, phospholipase C gamma2, as well as Grb2 and Nck adaptor proteins, thus represents a central linker protein that bridges the BCR-associated kinases with a multitude of signaling pathways. |
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| Immunogen | A fusion protein representing amino acids 171-356 of human BLNK. |
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| Other Names | BLNK|blnk|MGC147045|BASH|Bca|Ly-57|Ly57|Lyw-57|SLP-65|AGM4|BLNK-S|LY57|SLP65|bca |
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| Gene, Accession # | Gene ID: 17060 |
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| Catalog # | ABIN94495 |
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| Price | |
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| Order / More Info | B-Cell Linker (BLNK) (aa 171-356) Antibody from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | PubMed: 16585544, 16493428, 12835482, 11449370, 9697839 |
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| 产品资料 |
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