| 产品详情 |
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| Antigenic Specificity | B-Cell Linker (BLNK) |
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| Clone | 5G9 |
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| Host Species | Mouse |
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| Reactive Species | human, mouse |
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| Isotype | IgG1 |
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| Format | ascites |
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| Size | 100 µL |
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| Concentration | n/a |
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| Applications | ELISA,Flow Cytometry (FACS),Immunocytochemistry (ICC),Immunohistochemistry (IHC),Western Blotting (WB) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | This gene encodes a cytoplasmic linker or adaptor protein that plays a critical role in B cell development. This protein bridges B cell receptor-associated kinase activation with downstream signaling pathways, thereby affecting various biological functions. The phosphorylation of five tyrosine residues is necessary for this protein to nucleate distinct signaling effectors following B cell receptor activation. Mutations in this gene cause hypoglobulinemia and absent B cells, a disease in which the pro- to pre-B-cell transition is developmentally blocked. Deficiency in this protein has also been shown in some cases of pre-B acute lymphoblastic leukemia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
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| Immunogen | Purified recombinant fragment of human BLNK expressed in E. coli. |
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| Other Names | BLNK|blnk|MGC147045|BASH|Bca|Ly-57|Ly57|Lyw-57|SLP-65|AGM4|BLNK-S|LY57|SLP65|bca |
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| Gene, Accession # | Gene ID: 29760,17060 |
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| Catalog # | ABIN968984 |
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| Price | |
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| Order / More Info | B-Cell Linker (BLNK) Antibody from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | PubMed: 19218240, 19018766 |
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| 产品资料 |
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