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Antigenic Specificity | Notch, extracellular domain, EGF repeats #5-7 |
Clone | F461.3B |
Host Species | Mouse |
Reactive Species | Drosophila |
Isotype | IgG1 |
Format | supernatant |
Size | 1.0 ml |
Concentration | n/a |
Applications | Immunofluorescence, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Epitope: extracellular domain, EGF repeats #5-7 [see depositor notes]. This antibody was generated against the extracellular domain of Notch containing the EGF repeats # 5-7. The Neurogenic locus Notch protein functions as a transmembrane receptor for membrane-bound ligands Delta and Serrate to regulate neurodevelopment. Upon ligand activation, the intracellular domain (NICD) is released from the cell membrane, and forms a transcriptional activator complex with the Suppressor of hairless protein. |
Immunogen | Recombinant fusion protein containing the EGF repeats #5-7: Partial protein |
Other Names | CG3936, Notch, NECD, NICD |
Gene, Accession # | N, Gene ID: 31293, UniProt: P07207 |
Catalog # | F461.3B |
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Order / More Info | Notch, extracellular domain, EGF repeats #5-7 Antibody from DEVELOPMENTAL STUDIES HYBRIDOMA BANK |
Product Specific References | PubMed: 10669757, 17287246, 10862754, 14627723, 19064670, 18474623, 10669757, 16757030, 24286475 |
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