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| Antigenic Specificity | Discs, Large Homolog 4 (Drosophila) (DLG4) (N-Term) |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, rat, mouse |
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| Isotype | n/a |
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| Format | serum |
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| Size | 100 µL |
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| Concentration | n/a |
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| Applications | Immunohistochemistry (IHC),Western Blotting (WB) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Function: Interacts with the cytoplasmic tail of NMDA receptor subunits and shaker-type potassium channels. Required for synaptic plasticity associated with NMDA receptor signaling. Overexpression or depletion of DLG4 changes the ratio of excitatory to inhibitory synapses in hippocampal neurons. May reduce the amplitude of ACCN3 acid-evoked currents by retaining the channel intracellularly. May regulate the intracellular trafficking of ADR1B.Subcellular location: Cell membrane, Peripheral membrane protein. Cell junction ?? synapse ?? postsynaptic cell membrane ?? postsynaptic density. Cell junction ?? synapse. Cell junction ?? synapse ?? synaptosome. Note: High levels in postsynaptic density of neurons in the forebrain. Also in presynaptic region of inhibitory synapses formed by cerebellar basket cells on axon hillocks of Purkinje cells.Tissue specificity: Brain Also known as: Disks large homolog 4, Postsynaptic density protein 95, PSD-95, Synapse-associated protein 90, SAP-90, SAP90, DLG4. |
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| Immunogen | A synthetic peptide from n-terminal region of human PSD95 (DLG4, SAP-90) conjugated to an immunogenic carrier protein was used as the antigen. |
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| Other Names | 11|CG1725|CG1730|CPD|DLG|DLG-A|Discs-large|Dlg|Dlg-A|Dlg1|DlgA|Dmel\\CG1725|Drodlg|PSD95|SAP97|anon-EST:Posey93|anon-WO03040301.258|anon-WO03040301.260|anon-WO03040301.268|d. lg.-1|dlg|dlg-1|dlg-A|dlgA|dlgS97|l(1)10Bf|l(1)G0276|l(1)G0342|l(1)G0456|l(1)G19|l(1)L11|l(1)bwn|l(1)d.lg-1|l(1)d.lg.-1|l(1)discs large|l(1)dlg|l(1)dlg-1|l(1)dlg1|l(1)l.pr.-2|l(1)lpr-2|misb|dlgh4|psd95|sap90|sap-90|LLGL1|Dlgh4|PSD-95|SAP90|SAP90A|Sap90|SAP-90|DLG4 |
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| Gene, Accession # | Gene ID: 1742,13385,29495 |
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| Catalog # | ABIN571846 |
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| Price | |
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| Order / More Info | Discs, Large Homolog 4 (Drosophila) (DLG4) (N-Term) Antibody from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | n/a |
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