| 产品详情 |
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| Antigenic Specificity | E2F Transcription Factor 1 (E2F1) (aa 69-223) |
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| Clone | 8G9 |
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| Host Species | Mouse |
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| Reactive Species | human, mouse |
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| Isotype | IgG1 |
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| Format | purified |
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| Size | 0.1 mg |
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| Concentration | n/a |
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| Applications | ELISA,Flow Cytometry (FACS),Immunohistochemistry (IHC),Western Blotting (WB) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | The protein encoded by this gene is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionally conserved domains found in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. This protein and another 2 members, E2F2 and E2F3, have an additional cyclin binding domain. This protein binds preferentially to retinoblastoma protein pRB in a cell-cycle dependent manner. It can mediate both cell proliferation and p53-dependent/independent apoptosis. |
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| Immunogen | Purified recombinant fragment of human E2F1 (AA 69-223) expressed in E. coli. |
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| Other Names | CG6376|DRTF1/E2F|DmE2F-1|Dmel\\CG6376|Dp|E(Sev-CycE)3A|E(var)3-93E|E(var)3-95E|E(var)93E|E2F|E2F-1|E2F1|E2f1|Evar(3)164|dE2F|dE2F1|dE2f|dE2f1|de2f1|def21|drosE2F1|e2f|e2f1|l(3)07172|l(3)j3B1|l(3)j3C2|l(3)rM729|RBAP1|RBBP3|RBP3|mKIAA4009|xE2F|ATE2FB|E2F TRANSCRIPTION FACTOR-1 E2F1|E2F transcription factor 1|E2FB|E2FB TRANSCRIPTION FACTOR |
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| Gene, Accession # | Gene ID: 1869,13555 |
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| Catalog # | ABIN969516 |
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| Price | |
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| Order / More Info | E2F Transcription Factor 1 (E2F1) (aa 69-223) Antibody from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | PubMed: 20631077, 20952509, 20423997 |
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