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Antigenic Specificity | E2F Transcription Factor 1 (E2F1) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | mouse, rat, human |
Isotype | n/a |
Format | affinity purified |
Size | 200 µg |
Concentration | n/a |
Applications | Western Blotting (WB),Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The E2F transcription factors are essential for regulation of the cell cycle. Physiological E2F is a heterodimer composed of an E2F subunit together with a DP subunit (3, 4). Six members of the E2F family have been identified, and each E2F subunit has a DNA binding and a dimerization domain. E2F-1 to -5 activate transcription. E2F-1 to -3 bind pRb, and E2F-4 and -5 bind p107 or p130, and these interactions are under cell cycle control. E2F-1 has oncogenic properties in vivo and in vitro. E2F-1 can induce apoptosis through p53-dependent and -independent mechanisms. E2F-1 is stress-responsive, and is regulated by a PI3-kinase-like kinase family such as the ATM/ATR kinases.Synonyms: E2F-1, RBAP1, RBBP3, RBP3 |
Immunogen | A synthetic peptide of human E2F1 |
Other Names | CG6376|DRTF1/E2F|DmE2F-1|Dmel\\CG6376|Dp|E(Sev-CycE)3A|E(var)3-93E|E(var)3-95E|E(var)93E|E2F|E2F-1|E2F1|E2f1|Evar(3)164|dE2F|dE2F1|dE2f|dE2f1|de2f1|def21|drosE2F1|e2f|e2f1|l(3)07172|l(3)j3B1|l(3)j3C2|l(3)rM729|RBAP1|RBBP3|RBP3|mKIAA4009|xE2F|ATE2FB|E2F TRANSCRIPTION FACTOR-1 E2F1|E2F transcription factor 1|E2FB|E2FB TRANSCRIPTION FACTOR |
Gene, Accession # | Gene ID: 1869,13555,399489 |
Catalog # | ABIN1514021 |
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Order / More Info | E2F Transcription Factor 1 (E2F1) Antibody from ANTIBODIES-ONLINE GmbH |
Product Specific References | n/a |
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