| 产品详情 |
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| Product Name | Within Bgcn Homolog (Drosophila) (WIBG) peptide |
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| Description | WIBG is a key regulator of the exon junction complex (EJC), a multiprotein complex that associates immediately upstream of the exon-exon junction on mRNAs and serves as a positional landmarks for the intron exon structure of genes and directs post-transcriptional processes in the cytoplasm such as mRNA export, nonsense-mediated mRNA decay (NMD) or translation. It acts as a EJC disassembly factor, allowing translation-dependent EJC removal and recycling by disrupting mature EJC from spliced mRNAs. Its association with the 40S ribosomal subunit probably prevents a translation-independent disassembly of the EJC from spliced mRNAs, by restricting its activity to mRNAs that have been translated. It interferes with NMD and enhances translation of spliced mRNAs, probably by antagonizing EJC functions. |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | Western Blotting (WB),Immunohistochemistry (IHC),Blocking Peptide (BP) |
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| Other Names | BEST:HL05757|CG10330|CG30176|Dmel\\CG30176|PYM|Pym|UD3|A030010B05Rik|zgc:65891|zgc:77281 |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | ABIN939860 |
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| Price | |
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| Order / More Info | Within Bgcn Homolog (Drosophila) (WIBG) peptide from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | n/a |
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