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| Product Name | Acid Sphingomyelinase Activity Colorimetric Assay Kit |
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| Description | Sphingomyelinase (SMase) cleaves sphingomyelin to produce phosphorylcholine and ceramide. The activation of SMase leads to increased production of ceramide, which acts as a lipid second messenger. There are five distinct types of SMases. Deficiency in Acid SMase (ASMase) leads to Niemann-Pick disease type A and B. BioVision's Acid Sphingomyleinase Activity Assay Kit provides a simple and sensitive method for measuring ASMase enzymatic activity using colorimetry (OD 570 nm). In this assay, ASMase converts its substrate, sphingomyelin to phosphorylcholine and ceramide at pH 5.0; subsequently, phosphorylcholine is utilized in a series of reactions culminating in color formation from a highly specific probe. This high-throughput adaptable assay |
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| Size | 100 assays |
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| Concentration | n/a |
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| Applications | • Measurement of ASMase activity in various tissues/cell extracts• Screening of ASMase inhibitors |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | K598-100 |
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| Order / More Info | Acid Sphingomyelinase Activity Colorimetric Assay Kit from BIOVISION, INC. |
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| Product Specific References | n/a |
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