产品名称 High-Mobility Group Box 1 (HMGB1) protein from ANTIBODIES-ONLINE GmbH
产品货号 ABIN1540834
产品价格 现货询价,电话:010-67529703
产品规格 10 µg
产品品牌 ANTIBODIES-ONLINE GmbH
产品概述
产品详情
Edit&nbsp
Product NameHigh-Mobility Group Box 1 (HMGB1) protein
DescriptionHigh-mobility group box 1 protein (HMGB1), previously known as HMG-1 or amphoterin, is a member of the high mobility group box family of non-histone chromosomal proteins. Human HMGB1 is expressed as a 30 kDa, 215 amino acid (aa) single chain polypeptide containing three domains: two N-terminal globular, 70 aa positively charged DNA-binding domains (HMG boxes A and B), and a negatively charged 30 aa C-terminal region that contains only Asp and Glu.4, 5 Residues 27 - 43 and 178 - 184 contain a NLS. Posttranslational modifications of the molecule have been reported, with acetylation occurring on as many as 17 lysine residues. HMGB1 is expressed at high levels in almost all cells. It was originally discovered as a nuclear protein that could bend DNA. Such bending stabilizes nucleosome formation and regulates the expression of select genes upon recruitment by DNA binding proteins.
Size10 µg
Concentrationn/a
Applicationsn/a
Other Nameshmgb1|amphoterin|hmg-1|hmg1|hmg3|sbp-1|HMGB1|HMG1|HMG3|SBP-1|DEF|HMG-1|Hmg1|p30|Ac2-008|ik:tdsubc_1a5|wu:fb23c02|xx:tdsubc_1a5|zgc:56110|zgc:77104|Hmgb1
Gene, Accession, CAS #Gene ID: 3146
Catalog #ABIN1540834
Price
Order / More InfoHigh-Mobility Group Box 1 (HMGB1) protein from ANTIBODIES-ONLINE GmbH
Product Specific Referencesn/a
产品资料