产品名称 High-Mobility Group Box 1 (HMGB1) (AA 2-89) protein (His tag) from ANTIBODIES-ONLINE GmbH
产品货号 ABIN2115512
产品价格 现货询价,电话:010-67529703
产品规格 10 µg
产品品牌 ANTIBODIES-ONLINE GmbH
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Product NameHigh-Mobility Group Box 1 (HMGB1) (AA 2-89) protein (His tag)
DescriptionHMGB1 belongs to the HMGB family and contains 2 HMG box DNA-binding domains. HMGB1 is a DNA binding proteins that associates with chromatin and has the ability to bend DNA. This nuclear protein organizes the DNA and regulates transcription. After binding HMGB1 bends the DNA, which conducts to the binding of other proteins. HMGB1 suports transcription of many genes in interactions with many transcription factors or cooperation nucleosoms looses packed DNA and increases the chromatin remodeling, contact with core histones changes the structure of nucleosoms. it involved in V(D)J recombination by acting as a cofactor of the RAG complex. The presence of HMGB1 in the nucleus depends on posttranslational modifications. When the protein is not acetylated, stays in the nucleus, but hyperacetylation on lysine residues occurs to translocation into the cytosol. Synonyms: High-mobility group protein B1, high-mobility group protein 1, HMG-1, amphoterin and HMGB1.
Size10 µg
Concentrationn/a
Applicationsn/a
Other Nameshmgb1|amphoterin|hmg-1|hmg1|hmg3|sbp-1|HMGB1|HMG1|HMG3|SBP-1|DEF|HMG-1|Hmg1|p30|Ac2-008|ik:tdsubc_1a5|wu:fb23c02|xx:tdsubc_1a5|zgc:56110|zgc:77104|Hmgb1
Gene, Accession, CAS #Gene ID: 3146
Catalog #ABIN2115512
Price
Order / More InfoHigh-Mobility Group Box 1 (HMGB1) (AA 2-89) protein (His tag) from ANTIBODIES-ONLINE GmbH
Product Specific Referencesn/a
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