产品名称 BRCA1 Antibody from CREATIVE DIAGNOSTICS
产品货号 CABT-BL468
产品价格 现货询价,电话:010-67529703
产品规格 n/a
产品品牌 CREATIVE DIAGNOSTICS
产品概述
产品详情
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Antigenic SpecificityBRCA1
Clonemonoclonal
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG1
Formatunconjugated
Sizen/a
Concentrationn/a
ApplicationsWB, IP
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DescriptionMouse Anti-Human BRCA1 monoclonal antibody for WB,IP. Inherited mutations in BRCA1 and this gene, BRCA2, confer increased lifetime risk of developing breast or ovarian cancer. Both BRCA1 and BRCA2 are involved in maintenance of genome stability, specifically the homologous recombination pathway for double-strand DNA repair. The BRCA2 protein contains several copies of a 70 aa motif called the BRC motif, and these motifs mediate binding to the RAD51 recombinase which functions in DNA repair. BRCA2 is considered a tumor suppressor gene, as tumors with BRCA2 mutations generally exhibit loss of heterozygosity (LOH) of the wild-type allele. [provided by RefSeq, Dec 2008]
ImmunogenFusion protein
Other Namesn/a
Gene, Accession #Gene ID: 672, UniProt: P38398
Catalog #CABT-BL468
Price
Order / More InfoBRCA1 Antibody from CREATIVE DIAGNOSTICS
Product Specific Referencesn/a
产品资料