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| Product Name | Recombinant Human Breast cancer metastasis-suppressor 1 (BRMS1), partial |
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| Description | Purity > 90% as determined by SDS-PAGE. MW: 54.3kDa. Partial: 1-235aa. N-terminal GST-tagged. Homo sapiens (Human). Transcriptional repressor. Down-regulates transcription activation by NF-kappa-B by promoting the deacetylation of RELA at 'Lys-310'. Promotes HDAC1 binding to promoter regions. Down-regulates expression of anti-apoptotic genes that are controlled by NF-kappa-B. Promotes apoptosis in cells that have inadequate adherence to a substrate, a process called anoikis, and may thereby inhibit metastasis. May be a mediator of metastasis suppression in breast carcinoma. |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | RUO |
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| Other Names | n/a |
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| Gene, Accession, CAS # | BRMS1, UniProt: Q9HCU9 |
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| Catalog # | RPC24065 |
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| Price | |
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| Order / More Info | Recombinant Human Breast cancer metastasis-suppressor 1 (BRMS1), partial from BIOMATIK |
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| Product Specific References | n/a |
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