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| Product Name | sFas Receptor, human recombinant |
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| Description | Fas and Fas Ligand (FasL) belong to the TNF superfamily and are type I and type II transmembrane proteins, respectively. Binding of FasL to Fas triggers apoptosis in Fas-bearing cells. The mechanism of apoptosis involves recruitment of pro-caspase 8 through an adaptor molecule called FADD followed by processing of the pro-enzyme to active forms. These active caspases then cleave various cellular substrates leading to the eventual cell death. sFasR is capable of inhibiting FasL induced apoptosis by acting as a decoy receptor that serves as a sink for FasL. The full length Fas (receptor) is a 319 amino acid type I transmembrane protein, which contains a 157 amino acid extracellular domain, a 17 amino acid transmembrane domain, and 145 amino a |
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| Size | 10 µg |
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| Concentration | n/a |
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| Applications | RUO |
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| Other Names | soluble Fas receptor (sFasR), TNFRSF6, CD95, Apo I, Fas Antigen |
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| Gene, Accession, CAS # | FASL, Gene ID: 355, Accession: P25445 |
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| Catalog # | 7141-10 |
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| Order / More Info | sFas Receptor, human recombinant from BIOVISION, INC. |
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| Product Specific References | n/a |
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