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| Product Name | Defensin, beta 4A (DEFB4) (Active) protein |
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| Description | Defensins (alpha and beta) are cationic peptides with a broad spectrum of antimicrobial activity that comprise an important arm of the innate immune system. The α-defensins are distinguished from the beta-defensins by the pairing of their three disulfide bonds. To date, four human beta-defensins have been identified, BD-1, BD-2, BD-3 and BD-4. beta-defensins are expressed on some leukocytes and at epithelial surfaces. In addition to their direct antimicrobial activities, they are chemoattractant towards immature dendritic cells and memory T cells. The beta-defensin proteins are expressed as the C-terminal portion of precursors and are released by proteolytic cleavage of a signal sequence and, in the case of BD-1 (36 a.a.), a propeptide region. beta-defensins contain a six-cysteine motif that forms three intra-molecular disulfide bonds. beta-Defensins are 3-5 kDa peptides ranging in size from 33-47 amino acid residues. Synonym: beta-Defensin 2 (BD-2), Human. Formulation: Lyophilized from a 0.2µm filtered concentrated solution in 20mM PB, pH 7.4, 130mM NaCl. |
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| Size | 1 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | THP2|DEFB104|DEFB104B|DEFB4|DEFB102|BD-2|BD2|DEFB2|DEFB-2|HBD-2|SAP1|DEFB4P|BNBD-2|BNDB-2 |
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| Gene, Accession, CAS # | Gene ID: 1673 |
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| Catalog # | ABIN987770 |
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| Order / More Info | Defensin, beta 4A (DEFB4) (Active) protein from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | n/a |
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