| 产品详情 |
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| Product Name | HMG-CoA Reductase Catalytic Domain (GST Tagged), human recombinant |
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| Description | HMG-CoA reductase (3-hydroxy-3-methyl-glutaryl-CoA reductase or HMGR) (EC 1.1.1.34) is a transmembrane protein involved in the mevalonate pathway, the metabolic pathway that produces cholesterol from acetyl-CoA. In an NADPH-dependent reaction, HMG-CoA reductase reduces HMG-CoA to generate mevalonate and CoA. Since HMG-CoA reductase catalyzes the rate limiting step in cholesterol synthesis, it is a primary target of a group of cholesterol-lowering drugs known as statins. Inhibition of HMG-CoA reductase induces expression of LDL receptors in the liver, which lowers plasma concentration of cholesterol. MW: 75.9 kDa (426-888 aa, NT GST Tag). Purity ≥90% |
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| Size | 500 µg |
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| Concentration | n/a |
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| Applications | RUO |
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| Other Names | 3-Hydroxy-3-methylglutaryl-CoA reductase, HMGR, HMGCR |
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| Gene, Accession, CAS # | HMGCR, Gene ID: 3156, Accession: P04035 |
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| Catalog # | 7841-500 |
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| Order / More Info | HMG-CoA Reductase Catalytic Domain (GST Tagged), human recombinant from BIOVISION, INC. |
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| Product Specific References | n/a |
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