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Product Name | Recombinant Human Tumor necrosis factor receptor superfamily member 1B protein (TNFRSF1B) (Active) |
Description | Purity > 97% as determined by SDS-PAGE and HPLC. MW: 20.0kDa. Partial: 23-206aa. tag-Free. Homo sapiens (Human). Receptor with high affinity for TNFSF2/TNF-alpha and approximately 5-fold lower affinity for homotrimeric TNFSF1/lymphotoxin-alpha. The TRAF1/TRAF2 complex recruits the apoptotic suppressors BIRC2 and BIRC3 to TNFRSF1B/TNFR2. This receptor mediates most of the metabolic effects of TNF-alpha. Isoform 2 blocks TNF-alpha-induced apoptosis, which suggests that it regulates TNF-alpha function by antagonizing its biological activity. {ECO:0000269|PubMed:12370298}. |
Size | 100ug |
Concentration | n/a |
Applications | RUO |
Other Names | Tumor necrosis factor receptor 2, Tumor necrosis factor receptor type II, TNF-RII, TNFR-II, p75 |
Gene, Accession, CAS # | TNFRSF1B,TNFBR,TNFR2, UniProt: P20333 |
Catalog # | RPC26718 |
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Order / More Info | Recombinant Human Tumor necrosis factor receptor superfamily member 1B protein (TNFRSF1B) (Active) from BIOMATIK |
Product Specific References | n/a |
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