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| Product Name | Recombinant Human Tumor necrosis factor receptor superfamily member 10B protein (TNFRSF10B) (Active) |
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| Description | Purity > 97% as determined by SDS-PAGE and HPLC. MW: 14.8kDa. Partial: 52-183aa. tag-Free. Homo sapiens (Human). Receptor for the cytotoxic ligand TNFSF10/TRAIL. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF-kappa-B. Essential for ER stress-induced apoptosis. {ECO:0000269|PubMed:15322075}. |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | RUO |
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| Other Names | Death receptor 5, TRAIL receptor 2, TRAIL-R2, CD antigen CD262, |
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| Gene, Accession, CAS # | TNFRSF10B,DR5,KILLER,TRAILR2,TRICK2,ZTNFR9,UNQ160/PRO186, UniProt: O14763 |
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| Catalog # | RPC26711 |
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| Price | |
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| Order / More Info | Recombinant Human Tumor necrosis factor receptor superfamily member 10B protein (TNFRSF10B) (Active) from BIOMATIK |
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| Product Specific References | n/a |
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