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| Product Name | Recombinant Human Tumor necrosis factor receptor superfamily member 1A (TNFRSF1A), partial |
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| Description | Purity > 90% as determined by SDS-PAGE. MW: 47.2kDa. Partial: 31-210aa. N-terminal GST-tagged. Homo sapiens (Human). Receptor for TNFSF2/TNF-alpha and homotrimeric TNFSF1/lymphotoxin-alpha. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Contributes to the induction of non-cytocidal TNF effects including anti-viral state and activation of the acid sphingomyelinase. |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | RUO |
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| Other Names | Tumor necrosis factor receptor 1; TNF-R1Tumor necrosis factor receptor type I; TNF-RI; TNFR-Ip55p60; CD120a |
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| Gene, Accession, CAS # | TNFRSF1A, UniProt: P19438 |
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| Catalog # | RPC24139 |
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| Price | |
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| Order / More Info | Recombinant Human Tumor necrosis factor receptor superfamily member 1A (TNFRSF1A), partial from BIOMATIK |
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| Product Specific References | n/a |
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