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Product Name | Recombinant Human Tumor necrosis factor receptor superfamily member 1A (TNFRSF1A), partial |
Description | Purity > 85% as determined by SDS-PAGE. MW: 22.7kDa. Partial: 22-211aa. C-terminal 6xHis-tagged. Homo sapiens (Human). Receptor for TNFSF2/TNF-alpha and homotrimeric TNFSF1/lymphotoxin-alpha. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases mediating apoptosis. Contributes to the induction of non-cytocidal TNF effects including anti-viral state and activation of the acid sphingomyelinase. |
Size | 100ug |
Concentration | n/a |
Applications | RUO |
Other Names | Tumor necrosis factor receptor 1 (TNF-R1) (Tumor necrosis factor receptor type I) (TNF-RI) (TNFR-I) (p55) (p60) (CD_antigen: CD120a) (TNFAR) (TNFR1) |
Gene, Accession, CAS # | TNFRSF1A, UniProt: P19438 |
Catalog # | RPC26157 |
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Order / More Info | Recombinant Human Tumor necrosis factor receptor superfamily member 1A (TNFRSF1A), partial from BIOMATIK |
Product Specific References | n/a |
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