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| Product Name | Recombinant Human Tumor necrosis factor receptor superfamily member 1A protein (TNFRSF1A) (Active) |
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| Description | Purity > 97% as determined by SDS-PAGE and HPLC. MW: 21.2kDa. Partial: 22-211aa. tag-Free. Homo sapiens (Human). Receptor for TNFSF2/TNF-alpha and homotrimeric TNFSF1/lymphotoxin-alpha. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Contributes to the induction of non-cytocidal TNF effects including anti-viral state and activation of the acid sphingomyelinase. |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | RUO |
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| Other Names | Tumor necrosis factor receptor 1, Tumor necrosis factor receptor type I, TNF-RI, TNFR-I, p55 |
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| Gene, Accession, CAS # | TNFRSF1A,TNFAR,TNFR1, UniProt: P19438 |
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| Catalog # | RPC26717 |
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| Order / More Info | Recombinant Human Tumor necrosis factor receptor superfamily member 1A protein (TNFRSF1A) (Active) from BIOMATIK |
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| Product Specific References | n/a |
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