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| Product Name | Recombinant Human Tumor necrosis factor receptor superfamily member 12A protein (TNFRSF12A) (Active) |
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| Description | Purity > 95% as determined by SDS-PAGE. MW: 84.63kDa. Partial: 18-740aa. C-terminal 6xHis-tagged. Homo sapiens (Human). Angiotensin-Converting Enzyme 2 (ACE-2) is an integral membrane protein and a zinc metalloprotease of the ACE family, the ACE family includes somatic and germinal ACE. ACE-2 cleaves angiotensins I and II as a carboxypeptidase, ACE-2 converts angiotensin I to angiotensin 1-9, and angiotensin II to angiotensin 1-7. ACE-2 is also able to hydrolyze apelin-13 and dynorphin-13 with high efficiency. ACE-2 can be high expressed in testis, kidney and heart, in colon, small intestine and ovary at moderate levels. Captopril and lisinopril as the classical ACE inhibitor don't inhibit ACE-2 activity. ACE-2 may play an important role in regulating the heart function. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | RUO |
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| Other Names | Angiotensin-Converting Enzyme 2; ACE-Related Carboxypeptidase; Angiotensin-Converting Enzyme Homolog; ACEH; Metalloprotease MPROT15; ACE2 |
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| Gene, Accession, CAS # | ACE2, UniProt: Q9BYF1 |
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| Catalog # | RPC27013 |
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| Order / More Info | Recombinant Human Tumor necrosis factor receptor superfamily member 12A protein (TNFRSF12A) (Active) from BIOMATIK |
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| Product Specific References | n/a |
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