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| Product Name | Recombinant Human Tumor necrosis factor protein (TNF) (Active) |
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| Description | Purity > 95% as determined by SDS-PAGE. MW: 41.3kDa. Partial: 19-134aa. C-terminal 6xHis-FC-tagged. Homo sapiens (Human). Activin proteins that belong to the transforming growth factor-beta (TGF-β) superfamily, exert their biological actions by binding to heteromeric receptor complexes of type I and type II serine/threonine kinase receptors. On ligand binding, type I and II receptors form a stable complex, resulting in phosphorylation of type I receptors by type II receptors with constitutive kinase activity, and subsequently initiates the activation of downstream molecules including the endogenous Smads. ActRIIB, also known as ActRIIB, is a type II receptor containing an extracellular domain (ECD), a transmembrane segment, and a cytoplasmic region that includes the kinase domain. ActRIIB is a receptor for activin A, activin B and inhibin A. Multiple ActRIIB isoforms can also be generated, which bind activin isoforms with different affinities. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | RUO |
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| Other Names | Activin Receptor Type-2B; Activin Receptor Type IIB; ACTR-IIB; ACVR2B |
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| Gene, Accession, CAS # | ACVR2B, UniProt: Q13705 |
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| Catalog # | RPC27016 |
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| Order / More Info | Recombinant Human Tumor necrosis factor protein (TNF) (Active) from BIOMATIK |
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| Product Specific References | n/a |
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