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Antigenic Specificity | Complement Component (3d/Epstein Barr Virus) Receptor 2 (CR2) |
Clone | LT21 |
Host Species | Mouse |
Reactive Species | human, porcine, cow, dog |
Isotype | IgG1 |
Format | fluorescein (FITC) conjugate |
Size | 100 tests |
Concentration | n/a |
Applications | Flow Cytometry (FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CD21 (complement receptor 2, CR2) binds C3 complement fragments, especially its breakdown fragments, which remain covalently attached to complement activating surfaces or antigen. CD21 has important roles in uptake and retention of immunocomplexes, survival of memory B cells and in development and maintenance of the humoral response to T-dependent antigens. CD21 also serves as a key receptor for Epstein-Barr virus binding and is involved in targeting prions to folicular dendritic cells and expediting neuroinvasion following peripheral exposure to prions. A soluble form of the CD21 (sCD21) is shed from the lymphocyte surface and retains its ability to bind respective ligands. |
Immunogen | IM9 human B-lymphoblastoid cell line |
Other Names | C3DR|CD21|CR|CVID7|SLEB9|cd21|Cd21|CD35|Cr-1|Cr-2|Cr1 |
Gene, Accession # | Gene ID: 1380,490269,100623585,407126 |
Catalog # | ABIN302019 |
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Order / More Info | Complement Component (3d/Epstein Barr Virus) Receptor 2 (CR2) Antibody from ANTIBODIES-ONLINE GmbH |
Product Specific References | PubMed: 17951165, 17379312, 17850488, 17098248, 17673300 |
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