产品详情 |
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Antigenic Specificity | CD49f |
Clone | 3H1515 |
Host Species | Rat |
Reactive Species | human monkey mouse porcine |
Isotype | IgG2a |
Format | phycoerythrin (PE) conjugate |
Size | 100ul |
Concentration | n/a |
Applications | FC IHC IP |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The monoclonal antibody is directed against the CDw49f-antigen, 120kD, (GP Ic or VLA-6 alpha-chain), which can form distinct complexes with either the CD29-antigen (GP 11a or VLA beta-chain), resulting in the VLA-6 (alpha-6 beta-1) complex, which is expressed on human platelets, or with the beta-4 integrin resulting in the alpha-6 beta-4 complex which is expressed on various human epithelial cells. The monoclonal antibody reacts with platelets, megakaryocytes, T lymphocytes and common Acute Lymphoblastic Leukaemia cells (alpha-6 beta-1). In Immunohistochemistry the monoclonal antibody reacts with epithelial cells of a variety of tissues, peripheral nerves, microvascular endothelial cells, placenta cyto- and syncytotrophoblasts. Platelet VLA-6 functions as a laminin receptor and platelet adhesion to laminin is inhibited by GoH3. Species Crossreactivity: Clone is reported to react with Cynomolgus monkey (8), mouse and porcine. |
Immunogen | BALB/c mouse mammary tumour cells. |
Other Names | CD49f (Laminin Receptor, Integrin alpha6, VLA alpha6, Platelet gpIc) (PE) |
Gene, Accession # | n/a |
Catalog # | C2405-04B-PE |
Price | |
Order / More Info | CD49f Antibody from UNITED STATES BIOLOGICAL |
Product Specific References | n/a |
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