| 产品详情 |
| Edit |   |
|---|
| Product Name | Recombinant Human Rab proteins geranylgeranyltransferase component A 1 (CHM) |
|---|
| Description | Purity > 90% as determined by SDS-PAGE. MW: 77.5kDa. Full Length: 1-653aa. N-terminal 6xHis-tagged. Homo sapiens (Human). Substrate-binding subunit of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B composed of RABGGTA and RABGGTB, and remains bound to it after the geranylgeranyl transfer reaction. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane. Besides, a pre-formed complex consisting of CHM and the Rab GGTase dimer (RGGT or component B) can bind to and prenylate Rab proteins; this alternative pathway is proposed to be the predominant pathway for Rab protein geranylgeranylation. |
|---|
| Size | 100ug |
|---|
| Concentration | n/a |
|---|
| Applications | RUO |
|---|
| Other Names | Choroideremia protein; Rab escort protein 1; Short name:REP-1; TCD protein |
|---|
| Gene, Accession, CAS # | CHM, UniProt: P24386 |
|---|
| Catalog # | RPC21093 |
|---|
| Price | |
|---|
| Order / More Info | Recombinant Human Rab proteins geranylgeranyltransferase component A 1 (CHM) from BIOMATIK |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|