产品详情 |
Edit |   |
Product Name | IACS-010759 |
Description | IACS-010759 is a potent and selective Oxidative Phosphorylation Inhibitor (IC50 < 10 nM) with potential antineoplastic activity. IACS-010759 robustly inhibits proliferation and induces apoptosis in models of brain cancer and acute myeloid leukemia (AML) reliant on OXPHOS, likely owing to a combination of energy depletion and reduced aspartate production that leads to impaired nucleotide biosynthesis. MW: 562.57. Purity ≥98% by HPLC |
Size | 5 mg |
Concentration | n/a |
Applications | n/a |
Other Names | 5-(5-methyl-1-(3-(4-(methylsulfonyl)piperidin-1-yl)benzyl)-1H-1,2,4-triazol-3-yl)-3-(4-(trifluoromethoxy)phenyl)-1,2,4-oxadiazole |
Gene, Accession, CAS # | CAS: 1570496-34-2 |
Catalog # | B2231-5 |
Price | |
Order / More Info | IACS-010759 from BIOVISION, INC. |
Product Specific References | n/a |
产品资料 |
|
|